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Gerard de Hert, EurGeol, Senior VP Exploration for Endeavour Mining, has reviewed and approved the technical information in this news release. Gerard de Hert has more than 20 years of mineral exploration and mining experience and is a "Qualified Person" as defined by National Instrument 43-101 – Standards of Disclosure for Mineral Projects ("NI 43-101").

OUT: Derrick Appiah (London Scottish), Tevita Cavubati (Newcastle Falcons), Mike Daniels (Hartpury College), Tiff Eden (Nottingham Rugby), James Johnston (Brive), Ryan Lamb (La Rochelle), Na’ama Leleimalefaga (Brive), Val Rapava Ruskin (Gloucester Rugby), Auguy Slowik (Northern Suburbs Rugby Club), Chris Vui (Bristol Rugby), Phil Dowson (retired), Andy Short (retired), Sam Betty, Tom Biggs, Connor Braid, Jaba Bregvadze, Ryan Grant, Cooper Vuna (all released).

An immediate medical benefit is the greatly reduced risk of a urinary tract infection (UTI), which is higher in infancy than any other year of life, and 10 times greater if the infant male is uncircumcised [21–26]. UTIs are common in uncircumcised infant boys [22–26] and cause severe pain. UTI as a cause of a fever at this age is often undiagnosed [27, 28]. Bacteriuria in febrile boys presenting at hospital emergency departments occurs in 36% of uncircumcised boys, pointing to a UTI as the likely cause of fever, compared with only 1.6% of boys who are circumcised [29]. Antibiotic resistance in pathogenic bacteria under the foreskin is a growing problem [30]. The younger the infant, the more likely and severe the UTI will be, and the greater the risk of sepsis and death [31]. In the still-growing pediatric kidney [26, 32] a UTI can result in permanent kidney damage in 34-86% of cases [33, 34], thus exposing the boy to serious, life-threatening conditions later in life [26], including end-stage renal disease in 10% of cases [35]. In men, risk of UTI is over 5-fold higher if they are uncircumcised [36]. Thus infant MC offers protection against UTI over the lifetime.

The reasons for MC given by Australian parents include family tradition, improved hygiene and reduced risk of diseases and other conditions that MC protects against [106]. A study of African-American parents found that 96% strongly believed pediatric circumcision to be healthy, and 73% considered it essential [107]. Interestingly, the study found that it was the mothers who most often made the final decision. This demonstrates the need to engage and educate mothers and pregnant women about MC for their infant boys.

When the three-foot rod is completely submerged in the dirt, operators disconnect the rod, spin the bar back up and connect another segment onto the drill.

Over the next decade, however, Bosch and his team overcame a multitude of technological and metallurgical challenges. He chronicled them in his 1932 acceptance speech for the Nobel Prize for Chemistry — an honor he won because the Haber-Bosch process, as it came to be known, changed the world. His breakthrough made possible the production of ammonia on an industrial scale, providing the world with cheap and abundant fertilizer. The scientist and historian Vaclav Smil called Haber-Bosch “the most important technical invention of the 20th century.” Bosch had effectively removed the historical bounds on crop yields, so much so that he was widely credited with making “bread from air.” By some estimates, Bosch’s work made possible the lives of more than two billion human beings over the last 100 years.

Circumcision predates human history, with evidence of MC from art forms of the Upper Paleolithic period in Europe (38,000 to 11,000 years BCE) [6]. Rather than arising independently in diverse cultures globally [7], the practice more logically arose prior to the migration of Homo sapiens out of Africa [8]. If it had no survival advantage, it is unlikely that it would have persisted, and, as hypothesized by Cox & Morris, subsequent cessation of MC in some populations was perhaps a result of behavioral changes caused by environmental stressors or new religious philosophies such as Hinduism and Buddhism [8]. Such factors could explain why circumcision is relatively low in European, South and Central America, southern Africa, and non-Muslim Asian countries.

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Notes available in Appendix 3 for the 2018 Mineral Reserves and Resources. For 2017 Reserves and Resource notes, please consult Company’s press releases dated March 13, 2018 available on the Company’s website.

The main focus is expected to continue to be near-mine exploration at Endeavour’s two flagship mines (Hounde and Ity) and continue to develop organic growth opportunities such as Kalana, Fetekro, and other greenfield properties.

- Mining is expected to continue in the Vindaloo deposit, while ore extraction at the Bouere deposit is expected to start in late H1-2019. The strip ratio is expected to increase in 2019, due to both the mine plan sequence and to the carry-over of stripping delayed from 2018.